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Nitrile vs latex gloves

One glove your whole team can wear

Latex fits like a second skin, but its proteins can cause allergic reactions in the people who wear it. Here is how nitrile compares on six points, so you can stock one glove that is safe for everyone.

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The Glove Zone
Hands in blue, purple, black and orange disposable gloves stacked together in a team huddle

Latex was the standard disposable glove for decades. It stretches, fits close and gives a fine sense of touch. It also carries natural rubber proteins that can cause allergic reactions, and ACAAI lists health care workers who often wear latex gloves among the people most likely to develop one. Buy for a clinic, a kitchen, a shop or a studio, and that risk covers every wearer on the shift and every person the gloves touch.

A nitrile glove has none of those proteins. We only sell latex-free gloves, so we have a side here. That is why every claim below points to a primary source: the FDA, OSHA, ACAAI or a published glove study. Where latex is the better material, we say so. Our nitrile mostly ships in cases of 1,000, in weights from 3 to 8 mil.

The short answer

Nitrile is the safer pick for most teams. It has no latex proteins, failed less often than latex in a study of more than 5,000 exam gloves, and holds up to oils and fuels. Latex still stretches more, so it suits crews where no wearer, patient or customer has a latex allergy.

Best disposable gloves for work

Our pick

We scored both materials from 1 to 10 on six points and averaged them. Nitrile lands at 8.0 and latex at 5.7. Nitrile takes four rounds: allergy risk, barrier strength, oils and grease, and gasoline and diesel. Latex keeps two: stretch and a renewable source. The scores are a buyer's guide, not a lab result. We weighted them toward what decides a glove order, which is who wears it, what it touches and how long it stays on.

Are nitrile and latex gloves the same? Not when you buy for a team. ACAAI advises that when a health care worker is sensitive to latex, their co-workers should switch to synthetic gloves too. One allergy changes the order for everyone, because gloves touch co-workers, patients and customers as well as the wearer.

Score8.0

Nitrile is the safer pick for teams

It wins on allergy risk, barrier strength, oils and fuels. Latex keeps the closer fit, which only matters once you know nobody on the job is allergic.

Nitrile vs latex glove spec sheet

Feature by feature

This sheet scores nitrile vs latex gloves in three groups: safety, the job and feel. A check means the material handles that point well, a dash means it gets by, and a cross means it struggles. The oil and fuel rows come from the glove chart in OSHA's PPE guide, and the failure rates come from a 2002 study of 5,510 exam gloves. Half the gloves went through a stress routine, and all were water-tested to FDA standards. After adjusting for brand and stress, latex gloves were about 3 times more likely to fail than nitrile (odds ratio 3.2).

Start with the allergy row. The ACAAI latex reaction overview explains that a latex glove allergy usually develops after many exposures, so the people who wear gloves all day carry the most risk. It also notes that hospitals using only non-latex and low-protein latex gloves saw dramatic declines in new cases. ACAAI adds that people with hay fever or certain food allergies, such as banana, avocado or kiwi, are at higher risk too. For most buyers comparing latex vs nitrile gloves, that row settles it.

Safety

Latex allergy
Nitrile: No natural rubber proteins
Latex: Proteins can cause reactions
Barrier in testing
Nitrile: 1.3% failed in testing
Latex: 2.2% failed in testing

On the job

Oils & grease
Nitrile: Very good on OSHA's chart
Latex: Poor on OSHA's chart
Gasoline & diesel
Nitrile: Very good on OSHA's chart
Latex: Poor on OSHA's chart

Feel & footprint

Stretch & fit
Nitrile: Snug, flexible fit
Latex: Most elastic, second skin
Renewable source
Nitrile: Made from synthetic rubber
Latex: Tapped from rubber trees
Black nitrile gloves applying film to a car headlight, the kind of wet shop work where nitrile holds up
Black nitrile gloves applying film to a car headlight, the kind of wet shop work where nitrile holds up

Who each glove type is best for

Pick by the job

The nitrile gloves vs latex choice gets simple once you know who the gloves will touch and what they will touch. OSHA asks employers to choose hand protection for the task, the conditions, how long the gloves are worn and the hazards involved. For clinics, dental offices and vet practices, start with our medical glove collection. Those are the rooms where a glove touches patients who may not know they are allergic. Tattoo studios and salons wipe down with alcohol all day, and OSHA's chart rates both materials very good on ethyl alcohol, so that job comes down to allergy risk and fit. Acetone is the exception: OSHA's chart rates latex very good on it and nitrile poor. For nail work or long acetone contact, check the chemical's SDS and choose a thicker nitrile or a chemical-rated glove, since OSHA notes that thicker glove material gives greater chemical resistance.

Latex free gloves are what we recommend when one box serves a whole crew, because nobody has to ask who is allergic. If oils or fuels are part of the work, go heavier: our Orange Diamond Grip weighs 8.6 grams, about 8 mil. You can shop latex free gloves by job, size and thickness. Sizes run XS to XXL depending on the style, and some XL cases hold 900 gloves instead of 1,000.

Choose nitrile for

  • Clinics & exam roomsThe FDA points latex-allergic patients and staff toward synthetic gloves like nitrile.
  • Auto, fuel & grease workOSHA's chart rates nitrile very good on gasoline, diesel and kerosene.
  • Food prepOur Black Nitrile Gloves (Industrial) meet 21 CFR 177.2600 for food contact.

Choose latex for

  • A crew with no latex allergyConfirmed for the wearers and for everyone the gloves touch.
  • Close-fit, low-oil tasksWhere stretch matters more than resistance to fuel or grease.
  • Acetone & ketone splashesLatex rates very good on OSHA's chart, nitrile poor. Check the SDS.

Nitrile & latex glove pros & cons

Where each one falls short

Stretch is what you give up. A nitrile glove fits snugly and flexes, but it never feels quite as elastic as latex. It starts in a factory, not on a rubber tree, and that is what keeps nitrile gloves latex free. Our blue exam grade nitrile is a thin 3 mil glove with textured fingertips, for the close touch people miss when they leave latex. Weight adds cost: that glove is $59.95 a case, and the 8 mil Orange Diamond Grip is $99.95.

Latex gives up more. Powder free latex gloves solve part of the problem, since ACAAI ties some severe reactions to latex proteins carried into the air by glove powder, and the FDA banned powdered patient exam gloves in a final rule published December 19, 2016. The proteins are still in the glove itself, so a powder-free latex glove is still latex. OSHA's guide makes the same point: latex gloves have caused allergic reactions in some people and may not suit every employee.

Nitrile gloves

Pros

  • No latex proteins, safe for latex allergies
  • Failed less often than latex in testing
  • Very good on oils, grease & fuels
  • Cases of 1,000 from $59.95

Cons

  • Less stretch than latex
  • Made from synthetic rubber, not a crop
  • Heavy-duty weights cost more per case

Latex gloves

Pros

  • The stretchiest, closest fit
  • Outstanding tensile strength, per OSHA
  • Handles water-based acids, alkalis & salts
  • Made from renewable tree sap

Cons

  • Proteins can cause allergic reactions
  • Poor on gasoline, diesel & oils
  • Failed more often than nitrile in testing

Nitrile & latex glove questions

What our customers ask

Short answers to what buyers ask us most when a team moves off latex. The medical details come from ACAAI and the FDA, and if you think you react to gloves, see an allergist before you choose one.

Is Nitrile Latex Free?

Yes. Nitrile is a synthetic rubber, and ACAAI notes that synthetic rubber does not trigger reactions in people allergic to natural rubber latex. Still read the box: the FDA requires medical glove packaging to name the materials used, so the material is printed on every case. Every glove we sell is latex-free and powder-free, including our nitrile, Nitro-V and vinyl gloves.

Is Nitrile the Same as Latex?

No. Latex is natural rubber from the sap of the Hevea brasiliensis tree, and its proteins cause latex allergy. Nitrile is a synthetic rubber with none of those proteins. Both stretch and both come in thin exam weights, but nitrile holds up better to oils and fuels, while latex stretches more. The two even look alike in the box, which is why the label matters.

What Does a Latex Glove Allergy Feel Like?

Within minutes of contact, ACAAI says, skin can itch, redden and swell where the glove touched. Some people get hives, a runny nose, wheezing or chest tightness, and severe cases can lead to anaphylaxis. A separate rash from glove chemicals shows up 1 to 3 days later as blisters on the back of the hands. An allergist can confirm it with a blood test. ACAAI's advice for workers who react is plain: stop wearing latex gloves.

Sources: ACAAI: Latex Allergy · FDA: Medical Gloves · OSHA 3151: Personal Protective Equipment · OSHA 29 CFR 1910.138 · Korniewicz et al., Am J Infect Control, 2002

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