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Are nitrile gloves latex free

Latex free, with one thing to check

Yes, nitrile gloves are made without natural rubber latex, the source of latex allergy. Here is what that covers, what it leaves out, and how to pick gloves when someone on your team reacts.

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The Glove Zone
Hands in blue disposable gloves hold a long-haired calico cat while a second person steadies it

People usually ask us this for a reason. A nurse broke out in hives, or a new hire mentioned a latex allergy. The answer is good news, with one detail to know before you order a case.

We sell nitrile, nitrile-vinyl and vinyl gloves, and no latex, so we have a side here. That is why the medical facts below come from allergy and safety sources (ACAAI, AAAAI, NIOSH, the FDA and NIH) and two peer-reviewed studies. This guide explains glove materials. It does not diagnose anything, so if you have had a reaction, talk to your doctor or an allergist before you choose a glove.

The short answer

Yes. Nitrile is a synthetic rubber with none of the natural rubber latex proteins behind latex allergy, and the FDA lists it among the glove materials for people who are allergic to latex. Nitrile gloves can still carry processing chemicals called accelerators, which cause a different, delayed skin rash in some wearers.

Why nitrile gloves contain no latex

Factory made, not tapped from a tree

Are nitrile gloves latex free?

Yes. Natural rubber latex is a tree sap, and nitrile is a synthetic rubber made from chemicals. A glove made of 100% nitrile has no latex in its recipe.

According to ACAAI, natural rubber latex comes from the sap of the rubber tree, Hevea brasiliensis. NIOSH describes latex allergy as a reaction to certain proteins in that rubber. ACAAI also notes that synthetic rubber made from chemicals does not trigger reactions in people allergic to natural rubber latex. Nitrile belongs to that synthetic group, which is why the FDA names it, along with PVC and polyurethane, as a material people with a latex allergy can choose instead.

So is nitrile latex free? The material is. What you need to trust is the label, since boxes of nitrile, latex and blends can look alike. The FDA requires makers of medical gloves to name the materials on the package. Buyers often ask, do nitrile gloves contain latex in small amounts? A glove labeled 100% nitrile is made without it, so check for those words on the box or the product page.

For our part, every one of our 10 nitrile gloves lists "100% Nitrile, powder-free, non-latex" in its specifications. That runs from our 3 mil blue exam grade nitrile at $59.95 a case to the 8 mil Orange Diamond Grip at $99.95.

Blue Nitrile Gloves (Medical), our 3 mil glove listed as 100% nitrile, powder-free and non-latex
Blue Nitrile Gloves (Medical), our 3 mil glove listed as 100% nitrile, powder-free and non-latex

Latex allergy basics for glove buyers

Three reactions, only one from latex

Not every glove rash is a latex allergy. NIOSH sorts reactions to latex gloves into three kinds, and only one comes from the latex proteins that nitrile avoids.

ReactionCaused byWhat it looks likeDoes nitrile avoid it?
Irritant contact dermatitisWearing gloves, and powder on themIrritated skin on the hands, not a true allergyNot by itself, any glove can irritate
Allergic contact dermatitisChemicals added during manufacturingEczema-like rash, 1 to 3 days laterNot always, nitrile uses them too
Latex allergyProteins in natural rubber latexHives, itching, runny nose, wheezing, in minutesYes, no latex proteins

A latex allergy usually develops after many exposures, so the people at highest risk are the ones who wear gloves all shift. ACAAI lists health care workers and others who often wear latex gloves, people who have had many surgeries, rubber industry workers, and people with hay fever or certain food allergies. For a fuller picture, read ACAAI on latex reactions, including the foods that can cross-react, such as banana, avocado and kiwi.

The workplace advice is direct. When a health care worker is sensitive to latex, ACAAI says their co-workers should switch to synthetic gloves too. Hospitals and clinics that moved to non-latex or low-protein latex gloves saw dramatic declines in new cases.

Latex allergy symptoms to watch for

What a reaction can look like

Latex allergy symptoms usually start within minutes of contact, per ACAAI and NIOSH, though NIOSH notes they can also show up hours later. The list below combines what ACAAI and NIH's MedlinePlus describe:

  • Itching, redness and swelling where the glove touched the skin
  • Hives
  • Stuffy or runny nose, watery and itchy eyes
  • Scratchy throat, wheezing, chest tightness or trouble breathing
  • Blisters or an eczema-like rash on the back of the hands 1 to 3 days after wearing rubber gloves, which ACAAI attributes to glove chemicals rather than latex proteins

Powder can carry the problem past the hands. ACAAI reports anaphylaxis and severe asthma from inhaling latex proteins in the air, and MedlinePlus notes that breathing in the powder on latex gloves can cause reactions. Every glove we sell is powder-free.

If you suspect a latex allergy, see a clinician rather than testing gloves on yourself. ACAAI says latex allergy is diagnosed with an allergy blood test, and AAAAI points to an allergist as the doctor best placed to confirm it and build a plan. Bring the glove box with you, so they can see what the glove is made of.

Can you be allergic to nitrile gloves

Yes, to what goes into them

The short version

You can react to nitrile gloves, but not because of latex. The chemicals most often named are rubber accelerators, which help the rubber set during manufacturing.

So can you be allergic to nitrile gloves? A 2021 review in Allergologie Select explains that accelerators speed up vulcanization, the step that cross-links rubber, and that they can cause contact allergy of the delayed type. The review notes they are often used in nitrile and latex gloves alike. A 2018 survey of 190 exam and surgical gloves sold in the US found carbamate accelerators in 90.5% of them and thiurams in 11, and concluded that most exam and surgical gloves use accelerators.

A nitrile allergy of this kind looks like the allergic contact dermatitis in the table above: a rash where the glove sat, showing up hours or days later. AAAAI puts that delayed rash usually within 12 to 48 hours, and ACAAI says 1 to 3 days.

The review also warns that a "hypoallergenic" label usually refers to the absence of latex proteins, and accelerators may still be present. The tests differ too. Latex allergy is checked with a blood test, while the review recommends patch testing to find or rule out an accelerator allergy. Tell your doctor exactly which gloves you wear.

Accelerator free nitrile gloves explained

What the label does & doesn't promise

Accelerator free nitrile gloves are made without those chemicals. They are a real category: the 2018 survey found 8 companies advertising accelerator-free gloves, and the 2021 review says the number of accelerator-free nitrile disposables has grown, most with short cuffs. Its authors knew of no thick-walled disposable gloves made without accelerators.

Here is where we stand, plainly. None of our 100% nitrile gloves claims to be accelerator-free. The words "free from latex and accelerators" appear on three of our product pages, and none of them is a 100% nitrile glove:

GloveMaterialWhat its page saysPer case
Blue Nitrile (Medical)100% nitrile, 3 milPowder-free, non-latex$59.95
Blue Nitro-V (Medical)Nitrile-vinyl hybridFree from latex and accelerators$58.95
Black Nitro-V (Industrial)Nitrile-vinyl hybridFree from latex and accelerators$58.95
Biomass Clear VinylVinylFree from latex, powder and accelerators$67.95
Blue Nitro-V (Medical), a nitrile-vinyl hybrid glove listed as free from latex and accelerators
Blue Nitro-V (Medical), a nitrile-vinyl hybrid glove listed as free from latex and accelerators

Nitro-V blends nitrile and vinyl, so it is a hybrid, not a 100% nitrile glove. The 2021 review notes that a vinyl and nitrile mix can be made without accelerators. Sizes on these three sell out at times, so check yours on the product page before you order.

Choosing non latex gloves for a team

One box the whole crew can wear

When you buy for a team, you are choosing for people whose allergies you may not know, and for the patients, clients and customers their hands touch. NIOSH recommends nonlatex gloves for tasks that are not likely to involve infectious materials, and AAAAI suggests substituting vinyl or nitrile gloves for latex. Non latex gloves take the latex question off the table for everyone.

  1. Stock latex free gloves as the default, so nobody has to disclose an allergy to get a safe pair.
  2. Match thickness to the job: 3 to 4 mil for exams, food prep and salon work, 5 to 5.5 mil for heavier tasks, 7 to 8 mil diamond grip for oily or wet shop work.
  3. Read the label for the material and "powder-free" before every reorder.
  4. Keep a second option, such as Nitro-V or vinyl, for anyone a clinician says reacts to accelerators.
  5. Send anyone with a new rash or hives to a doctor, and note which glove they wore.

For clinics, dental offices and vet practices, start with our medical glove collection, six gloves from $58.95 a case. For kitchens, our Black and Blue Nitrile Gloves (Industrial) state that they comply with 21 CFR 177.2600 for food contact. Most cases hold 1,000 gloves. Some XL cases hold 900.

You can shop all our latex free gloves by the case by job, size and thickness. Shipping is free on contiguous US orders for a limited time, and most orders are processed within 1 business day.

Latex free glove questions

What our customers ask

Quick answers to what buyers ask us about latex. If you have had a reaction to any glove, check with your doctor before you choose one.

Do nitrile gloves have latex?

No. A glove made of 100% nitrile is a synthetic rubber with no natural rubber latex, and ACAAI notes that synthetic rubber does not trigger latex allergy. Blends exist, so read the label. The FDA requires medical glove packaging to name the materials, and every nitrile glove we sell says 100% nitrile and non-latex.

Is nitrile latex free?

Yes. Nitrile contains none of the natural rubber proteins that cause latex allergy, and the FDA lists it as a glove material for people allergic to latex. It can still carry rubber accelerators, chemicals that cause a delayed rash in some wearers. If your hands react to nitrile, ask an allergist or dermatologist about patch testing.

Are vinyl gloves latex free too?

Yes. Vinyl is PVC, which the FDA names as a material for people with a latex allergy, and AAAAI suggests vinyl or nitrile gloves in place of latex. A 2021 review adds that disposable vinyl gloves can be an alternative for people sensitized to rubber accelerators, with less stretch than nitrile. Our Biomass clear vinyl is listed as free from latex, powder and accelerators.

Sources: ACAAI: Latex allergy · AAAAI: Latex allergy · NIOSH 98-113: Latex allergy, a prevention guide · FDA: Medical gloves · Hansen et al., Allergologie Select, 2021 · Goodier et al., Dermatitis, 2018

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